Subacute Sclerosing Panencephalitis (SSPE) - due to Lack of Complete Immunization?
نویسنده
چکیده
The child was admitted in the paediatric department with complaints of fits for one month and altered level of consciousness for two days prior to admission. Mother had also noticed changes in behaviour for one month. He became unusually frightened when he was alone and in a dark room. Fits were not controlled for two days when he came to Abbasi Shaheed hospital and child became drowsy. He was shifted to Paediatric Intensive Care Unit (PICU), Paediatric Unit II, Abbasi Shaheed Hospital.
منابع مشابه
Subacute sclerosing panencephalitis. Clinical aspects and prognosis. The Brazilian registry.
Subacute sclerosing panencephalitis (SSPE) is an inflammatory neurodegenerative disease related to the persistence of measles virus. Although its frequency is declining because of measles eradication, we still have some cases being diagnosed. With the aim to describe epidemiological aspects of SSPE in Brazil, we sent a protocol to Child Neurologists around the country, 48 patients were register...
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Studies on the immunoprecipitation of the proteins of several different measles and subacute sclerosing panencephalitis (SSPE) virus strains from lysates of infected cells have revealed a relative lack of antibodies to the nonglycosylated viral membrane protein (M) in the sera of patients with SSPE, in contrast to a high level of antibodies to other viral proteins. No evidence was found for the...
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Subacute sclerosing panencephalitis (SSPE) is a rare degenerative disease of the central nervous system that affects primarily children and adolescents. It is a late manifestation of measles virus infection. In a 20-year period (1965-85) there have been 26 cases of SSPE in Northern Ireland, a frequency of approximately one case per 1.2 million population per year. Males were affected more frequ...
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Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the ...
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Recent evidence has suggested that subacute sclerosing panencephalitis (SSPE) is due to temperate infection of the brain by a virus, probably measles virus (Symposium, 1968). In the majority of patients with SSPE, chemical analysis of the brain has shown features of inflammation and demyelination (Cumings, 1965), though 2 patients have been described previously whose brains had abnormal pattern...
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