Prediction of occult cervical lymph node metastasis in clinically negative supraglottic squamous cell carcinoma

For citation purposes: Zeng R, Dai Q, Peng Z, Cai P, Hu W. Prediction of occult cervical lymph node metastasis in clinically negative supraglottic squamous cell carcinoma. Head Neck Oncol. 2012 Oct 27;4(3):69. Licensee OA Publishing London 2012. Creative Commons Attribution License (CC-BY) Abstract Objective Supraglottic laryngeal carcinomas are often accompanied by occult cervical lymph node metastasis. The aim of this study was to explore predictive factors of cervical lymph node metastasis in clinically negative supraglottic squamous cell carcinoma. Methods and materials From January 1990 to December 2009, a series of 221 patients with clinically negative cervical nodal metastases in supraglottic laryngeal squamous cell carcinoma were treated at Sun Yat-sen University Cancer Center. The overall survival rate and occult cervical lymph node metastasis-free survival rate were calculated using a life-table method. The survival curves were constructed by the Kaplan–Meier method and compared using a log-rank test. The relative significant factors in predicting occult cervical lymph node metastasisfree survival were assessed by multivariate Cox proportional hazards model. Results The 5-year overall survival rate in 221 patients was 58.6%. The 5-year overall survival rates of the positive cervical lymph node metastasis group Prediction of occult cervical lymph node metastasis in clinically negative supraglottic squamous cell carcinoma