Multiple complications in sickle cell anaemia.
نویسندگان
چکیده
Sickle Cell Disease (SCD) is a structural haemoglobinopathy which is extremely diverse in its presentation regarding disease severity and organ involved. The homozygous form if poorly managed gives rise to numerous life threatening conditions which are otherwise avoidable. Here we report the case of a male adolescent with homozygous SCD who presented with haemolytic anaemia, massive ascites, hepatomegaly and multiple fractures secondary to severe malnourishment associated with the disease.
منابع مشابه
Antioxidant Enzymes and Acute Phase Proteins Correlate with Marker of Lipid Peroxide in Adult Nigerian Sickle Cell Disease Patients
Objective(s) Sickle cell disease is a genetic disorder characterized by chronic haemolytic anaemia. Haemoglobin S containing red blood cells may be susceptible to oxidative stress due to imbalance between production of reactive oxygen species and the countering effect of the various antioxidants present in the body. Materials and Methods We evaluated some antioxidant enzymes which include gl...
متن کاملEffect of Lisinopril on Microalbuminuria in Sickle Cell Anaemia Children: A Single-Blind Randomized Controlled Trial
Background Sickle cell nephropathy is a major cause of morbidity and mortality in sickle cell anaemia (SCA). Proteinuria contributes to progression of renal damage. Icroalbuminuria is an early feature of SCN and progression to advanced kidney damage is delayed if regression is achieved with angiotensin converting enzyme inhibitors. We aimed to ...
متن کاملDigestive system complications among hospitalized children with sickle cell anaemia in Enugu, Nigeria
DISCLOSURES: NONE ABSTRACT Background: Sickle cell anaemia is a multi-systemic disease with variable clinical manifestations including those involving the digestive system. There is paucity of data on the digestive system complications of sickle cell anaemia in children in our setting. Objective: To determine the pattern of digestive system complications among hospitalized children with sickle ...
متن کاملAbsorption Spectra of Normal Adults and Patients with Sickle Cell Anaemia Haemoglobins Treated with Hydrogen Peroxide at Two pH Values
Background: The aim of the present study was application of haemoglobin absorption spectroscopy as a distinguishing tool for identification of two haemoglobin types-HbA and HbS. Material and Methods: Millimolar absorptivities of normal adult haemoglobin (HbA) and sickle cell haemoglobin (HbS) were monitored at pH values of 7.2 and 5.0, within the ultra violet and visible spectral range (250-...
متن کاملMultiple Complications in a Sickle Cell Disease Patient: A Case Report
Summary This case report illustrates the multiple complications experienced by a sickle cell anaemia patient. Although he enjoyed fairly good health till age 16 years; he subsequently suffered grade four bilateral femoral head necrosis, cerebella infarct and cerebral atrophy from cumulative effect of repetitive vasoocclussion, recurrent overwhelming septicaemia, fixed flexion deformities and de...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- JPMA. The Journal of the Pakistan Medical Association
دوره 68 1 شماره
صفحات -
تاریخ انتشار 2018