Protein complex membership estimation using apComplex
نویسنده
چکیده
apComplex contains functions for estimating protein complex membership using data from affinity-purification/mass-spectrometry (AP-MS) experiments. Users must specify the believed sensitivity and specificity of the AP-MS technology and may incorporate external similarity data for the proteins under investigation. The statistical details of the algorithm are reported in Scholtens and Gentleman (2004) and the biological implications are discussed in Scholtens, Vidal, and Gentleman (2005).
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