Protein Flexibility (3): ROCK and FRODA
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چکیده
This lecture talked about two examples of using FIRST to explore protein flexibility: ROCK [1, 2] and FRODA [3]. 1 The ROCK Algorithm 1.1 Terminology Ring: A closed loop of bonds in which any two atoms are connected by two distinct paths. Interlocked rings: Two rings that share common bond(s). Ring cluster: A collection of rings that are interlocked with one another. Side branches: All atoms that do not belong to any ring cluster. Figure 1 shows examples of ring, interlocked ring, ring cluster and side branch. Figure 1: Examples of ring, interlocked ring, ring cluster and side branch.
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