Conformational stability studies of a stapled hexa-β3-peptide library.
نویسندگان
چکیده
A library of 14-helical hexa β(3)-peptides was synthesized in order to determine the influence of sequence variation as well as staple size and location on conformational stability. From this study we show that appropriately stapled hexa-β(3)-peptides can allow for a number of variations without significant perturbation of the 14-helix.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 9 شماره
صفحات -
تاریخ انتشار 2012