Aldosterone blockade in cardiovascular disease.

Correspondence to: Professor Allan D Struthers, Division of Medicine & Therapeutics, Ninewells Hospital & Medical School, Dundee, DD1 9SY, UK; [email protected] _________________________ I t was once thought that aldosterone was a hormone released purely from the adrenal cortex, which circulated in the bloodstream and acted only on the kidneys to retain sodium and excrete potassium. This is now recognised to be a gross oversimplification (table 1).