Clinical updates on diagnosing glutensensitive enteropathy
نویسندگان
چکیده
In the last twenty years serology for the diagnosis of coeliac disease has improved substantially. As the result of our serological studies in 1998 we proposed a gentle, low-risk, and cost eff ective algorithm for diagnosing various forms of gluten sensitive enteropathy, using a combination of diff erent antibody determinations, namely IgA Endomysium antibodies (EMA), Tissue-transglutaminase antibodies (IgA anti tTG, IgG anti tTG), IgA-and IgG antigliadin-antibodies. Performing routinely serologic testing contributes to a decreased rate of endoscopic interventions and improves the quality of the patient’s life.
منابع مشابه
Gluten-sensitive enteropathy: Synthesis
The intestinal mucosa of patients with gluten-sensitive enteropathy responds to gluten challenge in vivo with a striking increase in IgA and IgM synthesis. Whether this increase in immunoglobulin synthesis is due in some part to the production of antigliadin antibodies is examined. Using an affinity chromatography technique it has been demonstrated that in six of seven patients with gluten-sens...
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