Characterisation of proposed reference materials for pertussis antiserum (human) by an international collaborative study
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Characterization of reference materials for human antiserum to pertussis antigens by an international collaborative study.
Enzyme-linked immunosorbent assay (ELISA) has been widely used to evaluate antibody responses to pertussis vaccination and infection. A common reference serum is essential for the standardization of these assays. However, no internationally recognized reference serum is available. At the request of the Expert Committee on Biological Standardization (ECBS) of the World Health Organization (WHO),...
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