The Action of Corticotropin (acth) on Nucleic Acids and Subcellular Elements of the Adrenal Cortex

Of Acth on Nucleic

Hormones are thought to regulate the functions of various tissues by forming complexes with enzymes or their inhibitors and thus inhibiting or enhancing enzymatic activity. The action of the so called trophic hormones of the anterior pi tui tary gland is of special interest, because they may stimulate hypertrophy and hyperplasla of certain organs such as gonads, adrenals, thyroid, and mammary g...

Exposure to cell phone radiofrequency changes corticotrophin hormone levels and histology of the brain and adrenal glands in male Wistar rat

Objective(s): Nowadays, the electromagnetic field-emitting devices are used routinely in our lives. Controversial reports exist concerning the effects of mobile radiofrequency (RF) on different parts of the body, especially stress hormones. The main goal of the present work was to study the long-term effects of mobile RF900 MHz exposure with special focus on the adrenal gland pathophysiology an...

Localization of an adrenocorticotropic hormone receptor on bovine adrenal cortical membranes.

The preparation of a subcellular fraction from bovine adrenal cortex is described. Characterization by electron microscopy, electron microscopic cytochemistry, and enzymatic assay indicates that this fraction is enriched plasma membranes. The preparation binds the steroidogenically active [Gin”] [W-Phe7] corticotropin, -ED amide. The specificity of this binding is demonstrated by competitive bi...

Contrasting requirements for the lipolytic action of corticotropin and epinephrine on adipose tissue in vitro.

Corticotropin, epinephrine, and norepinephrine are capable of promoting rapid breakdown of neutral fat within isolated rat adipose tissue (l-3). Within a few minutes of exposure to these hormones nonesterified fatty acids accumulate within the tissue and subsequently pass into the medium, provided albumin is present to serve as a carrier. Evidence has already been presented to indicate that the...

ACTH Adrenocorticotropic hormone CRF/CRH Corticotrophin releasing factor/hormone DALY Disability-adjusted life years DHEA Dehydroepiandrosterone DHEAS Dehydroepiandrosterone sulfate DNA Deoxyribose nucleic acid FSH Follicle stimulating hormone GH Growth hormone GHRH Growth hormone releasing hormone GnRH Gonadotropin releasing hormone HPA Hypothalamo–pituitary–adrenal axis