Studying Virus Cell Interactions: Finding New Ways to Prevent lnfectious Bovine Rhinotracheitis in Cattle
ثبت نشده
چکیده
lnfectious Bovine Rhinotracheitis (IBR; bovine herpesvirus 1 (BHV-1); Rednose) is one of several cattle respiratory viruses that plays a large role in the shipping fever complex. One of the major problems with IBR is that like other herpesviruses, once animals are infected they carry the virus for life. Investigations in our laboratory have been aimed at understanding how the IBR virus gets into cells. By understanding the mechanism that the virus uses we hope to develop strategies to prevent IBR infection. Our investigations indicate that IBR grows only in actively growing cells like those found in the upper respiratory tract of cattle. We also know that IBR does not grow well in slow growing cells like those found in the brain.
منابع مشابه
Detection of antibody against infectious bovine rhinotracheitis glycoprotein gE in aborted cattle in Mashhad, Iran
Infectious Bovine Rhinotracheitis is a highly contagious disease caused by the bovine herpes virus-1 (BoHV-1), resulting in significant losses to livestock around the world. BoHV-1 is a major pathogen of cattle, primarily associated with respiratory/genital tract infections and abortion. In the present study, we determined the presence of antibodies in 120 serum samples of cattle with the histo...
متن کاملSeroepidemological Survey for Antibodies against Infectious Bovine Rhinotracheitis and Bovine Herpes 4 Viruses among Cattle in Different Provinces of Iran.
متن کامل
The association between serological titers in infectious bovine rhinotracheitis virus, bovine virus diarrhea virus, parainfluenza-3 virus, respiratory syncytial virus and treatment for respiratory disease in Ontario feedlot calves.
A seroepidemiological study of the association between antibody titers to infectious bovine rhinotracheitis, parainfluenza-3, bovine virus diarrhea and bovine respiratory syncytial viruses, and treatment for bovine respiratory disease was conducted. A total of 322 calves from five different groups were bled on arrival, then one month later all cases (cattle treated for bovine respiratory diseas...
متن کاملIsolation of Infectious Bovine Rhinotracheitis Virus in Cell Culture: (a Case Study)
Infectious bovine rhinotracheitis is an important disease of cattle with serious economic implications. The etiology is bovine herpes virus type-1 which leads to clinical to latent infections and abortions. In this study, an aborted bovine fetus was suspected of IBR infection. The virus was grown in cell line (MDBK) and cytopathic effect observed. CPE began at 12 hr post infection of cells and ...
متن کاملBovine herpes virus infections in cattle.
Bovine herpes virus 1 (BHV-1) is primarily associated with clinical syndromes such as rhinotracheitis, pustular vulvovaginitis and balanoposthitis, abortion, infertility, conjunctivitis and encephalitis in bovine species. The main sources of infection are the nasal exudates and the respiratory droplets, genital secretions, semen, fetal fluids and tissues. The BHV-1 virus can become latent follo...
متن کامل