Hepatic Mitochondrial Proteins in Effect of Acetyl - L - carnitine Congenitally JSMA Hyperammonemic spf Mice :
نویسنده
چکیده
The sparse-fur (spf) mutant mouse has an X-linked deficiency of hepatic ornithine transcarbamylase (OTC), and devetops hyperftmmonemia immediately after weaning and maintains it throughout its life span. We haye studied the effects of acetyl-L-carnitine (ALCAR) on the hepatic mitochondrial proteins of the chronicaJly hyperammonemic spf mice. Two different age groups of mice were studied, the weanlings (3 weeks) and the adult
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