Radiofrequency Ablation of the Renal Sympathetic Nerves as a Treatment for Resistant Hypertension
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منابع مشابه
Effects of Renal Denervation on Sympathetic Activation, Blood Pressure, and Glucose Metabolism in Patients with Resistant Hypertension
Increased central sympathetic drive is a hallmark of several important clinical conditions including essential hypertension, heart failure, chronic kidney disease, and insulin resistance. Afferent signaling from the kidneys has been identified as an important contributor to elevated central sympathetic drive and increased sympathetic outflow to the kidney and other organs is crucially involved ...
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A role for renal nerves in the regulation of renal function has been recognized since the time of Claude Bernard. It has also been clear that renal nerves have an intimate relationship with many forms of experimental hypertension, and surgical splancnicectomy, with consequent renal denervation, was a recommended form of therapy for hypertension in humans before the introduction of effective pha...
متن کاملThe temperature field simulation of radiofrequency catheter-based renal sympathetic denervation for resistant hypertension.
Renal sympathetic denervation (RSD) by the radiofrequency ablation was used to treat the resistant hypertension in clinic and has achieved curative effect. But the temperature distribution in the artery walls and the blood flow have not been investigated. Finite element method (FEM) based on Comsol Multiphysics 4.3a software was used to simulate the temperature distribution in the renal artery....
متن کاملEfficacy and safety of catheter-based radiofrequency renal denervation in stented renal arteries.
BACKGROUND In selected patients with hypertension, renal artery (RA) stenting is used to treat significant atherosclerotic stenoses. However, blood pressure often remains uncontrolled after the procedure. Although catheter-based renal denervation (RDN) can reduce blood pressure in certain patients with resistant hypertension, there are no data on the feasibility and safety of RDN in stented RA....
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The year of 2013 in cardiology has been eventful with significant advances described in many fields including cardiac pharmacology, coronary artery intervention, percutaneous aortic valve implantation, heart failure, and electrophysiology. Perhaps one of the most rapidly expanding areas is that of renal denervation therapy (RDT) for treatment of resistant hypertension. Catheter-based radiofrequ...
متن کاملDevice-based approaches for renal nerve ablation for hypertension and beyond
Animal and human studies have demonstrated that chronic activation of renal sympathetic nerves is critical in the pathogenesis and perpetuation of treatment-resistant hypertension. Bilateral renal denervation has emerged as a safe and effective, non-pharmacological treatment for resistant hypertension that involves the selective ablation of efferent and afferent renal nerves to lower blood pres...
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