DNA Motif Databases and Their Uses.

نویسنده

  • Gary D Stormo
چکیده

Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications.

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عنوان ژورنال:
  • Current protocols in bioinformatics

دوره 51  شماره 

صفحات  -

تاریخ انتشار 2015