Core-pulling salpingectomy: a novel surgery for hydrosalpinx prior to in vitro fertilization and embryo transfer

نویسندگان

  • Hong-Chu Bao
  • Xin-Rong Wang
  • Mei-Mei Wang
  • Cui-Fang Hao
چکیده

Objective: This study aims to investigate the effects of a new surgical procedure to treat hydrosalpinx prior to in vitro fertilization and embryo transfer (IVF-ET). Methods: Infertile females receiving treatment for hydrosalpinx (n=633) were divided into one treated group and two comparison groups. The treated group comprised patients received pretreatment with core-pulling salpingectomy (n=105). One comparison group comprised patients who had conventional salpingectomy prior to IVF-ET (n=104), and the other comparison group comprised those received IVF-ET without a prior history of hydrosalpinx (n=424). Outcome in the treated group, ovarian reserve, ovarian responsiveness, and conception rates were compared to the two untreated groups. Results: After core-pulling salpingectomy, antral follicle number, endocrine profile, total dosage of ovulation-inducing agents required for ovarian stimulation, estradiol level on the day of human chorionic gonadotropin administration, and the number of oocytes retrieved following core-pulling salpingectomy were significantly higher compared to conventional salpingectomy, but not different from women without hydrosalpinx. Patients who underwent core-pulling salpingectomy received IVF-ET and achieved an increased clinical conception rate compared to conventional salpingectomy, but the difference was not statistically significant. Conclusions: Laparoscopic core-pulling salpingectomy should be recommended for patients with hydrosalpinx before receiving IVF-ET. This procedure did not interfere with ovarian reserve or responsiveness, and improved the conception rate.

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تاریخ انتشار 2016