Direct and cost-efficient hyperpolarization of long-lived nuclear spin states on universal N2-diazirine molecular tags

Department of Chemistry, Duke University, Durham, NC 27708, USA. Department of Physics, Duke University, Durham, NC 27708, USA. Department of Mechanical Engineering andMaterials Science, DukeUniversity, Durham,NC27708, USA. Departments of Radiology and Biomedical Engineering, Vanderbilt University, Institute of Imaging Science, Nashville, TN 37232, USA. Departments of Radiology and Biomedical Engineering, Duke University, Durham, NC 27708, USA. *Correspondingauthor. E-mail:[email protected] (W.S.W.); [email protected] (Q.W.); [email protected] (T.T.) †These authors contributed equally to this work. ‡Present address: Surbeck Laboratory of Advanced Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA.