Using Enterprise MinerTM to Explore and Exploit Drug Discovery Data
نویسنده
چکیده
One of the biggest challenges in modern pharmaceutical drug discovery is the effective management and exploitation of research data. How can one find those relatively small nuggets of knowledge buried in the great morass of data being generated by High Throughput Screening systems? One potential answer is by using Enterprise MinerTM software! This talk will describe how it can be used to find structural features of potential drug molecules that appear to effect interesting (and useful) biological activity. It will be shown how one can use Enterprise MinerTM even at a very basic level to uncover potentially useful relationships that can be exploited to more rapidly find new therapeutic candidates. Special issues with respect to how to mathematically describe chemical structures will also be addressed. This talk is geared towards SAS users at the beginning to intermediate skill level.
منابع مشابه
Employing data mining to explore association rules in drug addicts
Drug addiction is a major social, economic, and hygienic challenge that impacts on all the community and needs serious threat. Available treatments are successful only in short-term unless underlying reasons making individuals prone to the phenomenon are not investigated. Nowadays, there are some treatment centers which have comprehensive information about addicted people. Therefore, given the ...
متن کاملAn experimental comparison of classification techniques for imbalanced credit scoring data sets using SAS® Enterprise MinerTM
In this paper, we set out to compare several techniques that can be used in the analysis of imbalanced credit scoring data sets. In a credit scoring context, imbalanced data sets frequently occur as the number of defaulting loans in a portfolio is usually much lower than the number of observations that do not default. As well as using traditional classification techniques such as logistic regre...
متن کاملDrug Discovery Acceleration Using Digital Microfluidic Biochip Architecture and Computer-aided-design Flow
A Digital Microfluidic Biochip (DMFB) offers a promising platform for medical diagnostics, DNA sequencing, Polymerase Chain Reaction (PCR), and drug discovery and development. Conventional Drug discovery procedures require timely and costly manned experiments with a high degree of human errors with no guarantee of success. On the other hand, DMFB can be a great solution for miniaturization, int...
متن کاملSurvey on Perception of People Regarding Utilization of Computer Science & Information Technology in Manipulation of Big Data, Disease Detection & Drug Discovery
this research explores the manipulation of biomedical big data and diseases detection using automated computing mechanisms. As efficient and cost effective way to discover disease and drug is important for a society so computer aided automated system is a must. This paper aims to understand the importance of computer aided automated system among the people. The analysis result from collected da...
متن کامل