Innate Immunity: ER Stress Recruits NOD1 and NOD2 for Delivery of Inflammation

نویسندگان

  • Roberta Caruso
  • Gabriel Núñez
چکیده

NOD1 and NOD2, two members of the intracellular NOD-like receptor family, sense bacterial peptidoglycan-derived fragments and induce pro-inflammatory responses. Recent work provides evidence for a role for NOD1/NOD2 signaling in mediating ER-stress-induced inflammatory responses via a peptidoglycan-independent mechanism.

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عنوان ژورنال:
  • Current Biology

دوره 26  شماره 

صفحات  -

تاریخ انتشار 2016