Platelet Activation in Alzheimer’s Disease
نویسنده
چکیده
Platelets are small cellular fragments derived from megakaryocytes and circulate in the bloodstream at 250.000-400.000/μl. Platelets are responsible for hemostasis, but are also involved in thrombosis, inflammation and tissue repair. More importantly, recent evidence suggests a role for circulating platelets in Alzheimer’s disease (AD). Actually, platelets express and contain high amounts of amyloid precursor protein, APP (isoform 751 and 770).
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