1-Azido-N′-(phenylsulfonyl)methanimidamide
نویسندگان
چکیده
In the title compound, C(7)H(7)N(5)O(2)S, the aromatic ring is oriented at dihedral angles of 79.46 (2) and 89.17 (2)°, respectively, with respect to the amino-(azido)-methyl and the S(6) six-membered ring motif generated by an intra-molecular N-H⋯O inter-action [N⋯O = 2.8901 (15) Å]. Inter-molecular N-H⋯O hydrogen bonds [N⋯O = 2.9177 (15) and 2.9757 (15) Å] generate an infinite one-dimensional network along the base vector (010).
منابع مشابه
Synthesis , biological evaluation , and molecular docking of N ′ - ( Aryl / alkylsulfonyl ) - 1 - ( phenylsulfonyl ) piperidine - 4 - carbohydrazide derivatives
A series of new N ′ -[(alkyl/aryl)sulfonyl]-1-(phenylsulfonyl)piperidine-4-carbohydrazide derivatives were synthesized. Starting from ethyl piperidine-4-carboxylate (a), first ethyl 1-(phenylsulfonyl)piperidine-4-carboxylate (1), second 1-(phenylsulfonyl)piperidine-4-carbohydrazide (2), and finally N ′ -[(alkyl/aryl)sulfonyl]-1-(phenylsulfonyl)piperidine4-carbohydrazides (4a–n) were synthesized...
متن کاملSynthesis and anti-HBV activity of novel 3'-N-phenylsulfonyl docetaxel analogs.
Nine new 3'-N-phenylsulfonyl docetaxel analogs were synthesized in good yields from the key intermediate N-phenylsulfonyl oxazolidine via a six-step route. These analogs were tested for anti-hepatitis B virus (HBV) activity in vitro. Compounds 3e, 3g and 3j showed more potent inhibitory activity against HBeAg secretion than the positive control lamivudine. Further extensive SAR and mechanistic ...
متن کامل(Z)-2-(1-Phenylsulfonyl-1H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-one and (Z)-(S)-2-(1-phenylsulfonyl-1H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-ol.
The title compounds, C22H20N2O3S, (I), and C22H22N2O3S, (II), crystallize in space groups P-1 and P2(1)2(1)2(1), respectively. The indole rings are planar and the benzene ring of the phenylsulfonyl group makes a dihedral angle with the mean plane of the indole ring of 90.2 (2) degrees in (I) and 94.0 (2) degrees in (II). In both molecules, the double bond connecting the aza-bicyclic and indole ...
متن کاملA Simple Method for the Preparation of Cis-(3-Azido-4-Styryl)-2-Azetidinone
The synthesis of the title compound is described. Deprotection of Cis(N-Trityl-3-azido-4-Styryl)-2-azetidinone to Cis-(3-azido-4-styryl)-2-azetidinone was found to be accelerated by the special salt effect under acidic condition
متن کاملN-[(3-Phenylsulfanyl-1-phenylsulfonyl-1H-indol-2-yl)methyl]acetamide
In the title compound, C(23)H(20)N(2)O(3)S(2), the phenylsulfonyl ring and phenylthio ring make dihedral angles of 66.5 (7) and 81.2 (6)°, respectively, with the indole unit. In the crystal, mol-ecules are linked into centrosymmetric dimers via pairs of N-H⋯O hydrogen bonds with graph-set motif R(2) (2)(14). The crystal structure is further stabilized by weak inter-molecular C-H⋯O and very weak...
متن کامل