Swine- Origin Influenza A (H1N1) Pandemic Revisited
نویسندگان
چکیده
Since the beginning of January 2008 sporadic cases of infections in humans caused by influenza A (H1N1) virusresistant to available anti-influenza drugs have been reported worldwide [1,2]. The World Health Organization (WHO) in its report published on 18 March 2009 indicated that during weeks 1-4 (28 December 08-24 January 09), the level of overall influenza activity in the world increased. During this period, 1291 of 1362 A (H1N1) cases from 30 countries showed resistance to the antiviral drug osaltamivir. [3]. In Canada, United States of America, Japan, Republic of Korea, Hong Kong, France, Germany, Ireland, Sweden and United Kingdom the prevalence of oseltamivir resistance was reported to be more than 95% [3]. On 24 April WHO released the first alert indicating the occurrence of confirmed human cases of swine influenza (H1N1) in Mexico and the United States [4]. Subsequently the Centre for Disease Control and Prevention (CDC), in the United States confirmed that these human influenza cases were caused by a new strain of influenza A virus subtype (H1N1) [5]. A plethora of names was coined to describe the virus and outbreak ; "Swine flu", "Pig flu"," Mexican flu"," Mexican virus" , "H1N1 flu", "New flu", "North American influenza", and "Novel influenza A (H1N1)" to name a few [10]. "Swine flu names are evolving faster than the swine flu itself," says Martin Ensernick, the noted science reporter on the chaos over the nomenclature [13]. The WHO announced that they would refer to the new influenza virus as" Influenza A (H1N1)" or "Influenza A (H1N1) virus, human" as opposed to "swine flu" also to clear the misconception that eating pork products carried a risk of infection [14].
منابع مشابه
Rapid detection of reassortment of pandemic H1N1/2009 influenza virus.
BACKGROUND Influenza viruses can generate novel reassortants in coinfected cells. The global circulation and occasional introductions of pandemic H1N1/2009 virus in humans and in pigs, respectively, may allow this virus to reassort with other influenza viruses. These possible reassortment events might alter virulence and/or transmissibility of the new reassortants. Investigations to detect such...
متن کاملReassorted pandemic (H1N1) 2009 influenza A virus discovered from pigs in Germany.
A natural reassortant influenza A virus consisting of seven genome segments from pandemic (H1N1) 2009 virus and a neuraminidase segment from a Eurasian porcine H1N1 influenza A virus was detected in a pig herd in Germany. The obvious reassortment compatibility between the pandemic (H1N1) 2009 and H1N1 viruses of porcine origin raises concern as to whether swine may become a reservoir for furthe...
متن کاملOrigins of the 2009 H1N1 influenza pandemic in swine in Mexico
Asia is considered an important source of influenza A virus (IAV) pandemics, owing to large, diverse viral reservoirs in poultry and swine. However, the zoonotic origins of the 2009 A/H1N1 influenza pandemic virus (pdmH1N1) remain unclear, due to conflicting evidence from swine and humans. There is strong evidence that the first human outbreak of pdmH1N1 occurred in Mexico in early 2009. Howeve...
متن کاملApplying machine learning techniques to classify H1N1 viral strains occurring in 2009 flu pandemic
A phase 6 alert has been declared by the World Health Organization (WHO) in response to the ongoing global spread of the influenza H1N1 virus in humans. Genetic sequence analysis suggests that this pandemic strain evolves from reassortment of swine viruses. The objective of this research is to conduct a series of bioinformatics analyses to characterize currently circulating pandemic influenza v...
متن کاملrapidSTRIPE H1N1 test for detection of the pandemic swine origin influenza A (H1N1) virus.
The rapidSTRIPE H1N1 test, based on a nucleic acid lateral-flow assay, has been developed for diagnosis of a swine-origin influenza A (H1N1) virus. This test is simple and cost-effective and allows specific detection of the S-OIV A (H1N1) virus from swab sampling to final detection on a lateral-flow stripe within 2 to 3 h.
متن کامل