Copper-catalyzed electrophilic carbofunctionalization of alkynes to highly functionalized tetrasubstituted alkenes.
نویسندگان
چکیده
Copper catalysts enable the electrophilic carbofunctionalization of alkynes with vinyl- and diaryliodonium triflates. The new process forms highly substituted alkenyl triflates from a range of alkynes via a pathway that is opposite to classical carbometalation. The alkenyl triflate products can be elaborated through cross-coupling reactions to generate synthetically useful tetrasubstituted alkenes.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 135 14 شماره
صفحات -
تاریخ انتشار 2013