Osseointegration of Titanium Ti-6Al-4V Alloy Implants in the Rat Femur: A Time-course SEM Study
نویسندگان
چکیده
Biological fixation of uncemented endosseous implants requires the apposition of bone onto implant’s surface in a process named osseointegration [1]. The present study examined bone tissue response to Ti-6Al-4V alloy implanted into the rat femurs over a long time range (3 days to 6 months). The progression of implants fixation in the cancellous bone of distal epiphysis and within the medullary cavity of the rat femur was evaluated by SEM, oxytetracycline incorporation and ALP, TRAP and NSE histochemistry.
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