Women with prior preterm birth and short cervix: do NOT cerclage.
نویسنده
چکیده
THE ISSUE: Undeniably, the 2 major risk factors for preterm births, the bane of modern obstetrics, are history of spontaneous delivery 37 weeks and transvaginal cervical length 2.5 cm. A multicenter randomized clinical trial has evaluated the role of cerclage for women with these 2 risk factors and concluded that intervention is associated with improved outcomes. Despite the level I evidence for cerclage, there is controversy about when to cerclage and if 17-hydroxyprogesterone prophylaxis is sufficient.
منابع مشابه
P-188: Vaginal Progesterone Effects for The Prevention of Preterm Birth and Neonatal Complications in Women at Increased Risk: A Randomized Placebo- Controlled Double-Blind Study
Background: The purpose of this study was to evaluate the effect of prophylactic vaginal progesterone in decreasing preterm birth rate and neonatal complications in a high-risk population. Materials and Methods: A randomized, double-blind, placebo- controlled study included 100 high-risk singleton pregnancies( prior preterm birth,short cervix,uterine malformations and large intramural uterine m...
متن کاملAnother question for the list.
S chaaf and colleagues 1 have confirmed an increased risk of preterm birth in singleton pregnancies among women with a history of preterm birth in a twin pregnancy. Their comprehensive evaluation of a large dataset should settle the uncertainty that has attended previous smaller studies. 2-6 The risk is real, so now the question is, Why? Why do women who deliver twins preterm more often deliver...
متن کاملVaginal progesterone in risk reduction of preterm birth in women with short cervix in the midtrimester of pregnancy
Preterm birth is a major health problem for the neonate, family, country, and society in general. Despite many risk factors being identified for women destined to deliver preterm, short cervical length detected on transvaginal ultrasound is the most plausible, practical and sensitive risk factor for prediction of spontaneous preterm birth. The definition of short cervix has varied in various st...
متن کاملRaised Trappin2/elafin Protein in Cervico-Vaginal Fluid Is a Potential Predictor of Cervical Shortening and Spontaneous Preterm Birth
Early spontaneous preterm birth is associated with inflammation/infection and shortening of the cervix. We hypothesised that cervico-vaginal production of trappin2/elafin (peptidase inhibitor 3) and cathelicidin antimicrobial peptide (cathelicidin), key components of the innate immune system, are altered in women who have a spontaneous preterm birth. The aim was to determine the relationship be...
متن کاملPregnancy Outcomes after Treatment for Cervical Cancer Precursor Lesions: An Observational Study
OBJECTIVE To examine whether surgical procedures involving the uterine cervix were associated with pregnancy outcomes, including preterm birth, low birth weight, cesarean delivery and pregnancy loss. DESIGN Population-based observational study nested in retrospective matched cohort. SETTING Kaiser Permanente Northwest integrated health plan in Oregon/Washington, U.S.A. POPULATION Female h...
متن کاملVaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial.
OBJECTIVES Women with a sonographic short cervix in the mid-trimester are at increased risk for preterm delivery. This study was undertaken to determine the efficacy and safety of using micronized vaginal progesterone gel to reduce the risk of preterm birth and associated neonatal complications in women with a sonographic short cervix. METHODS This was a multicenter, randomized, double-blind,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- American journal of obstetrics and gynecology
دوره 205 2 شماره
صفحات -
تاریخ انتشار 2011