Multipotent Vasculogenic Pericytes from Human Pluripotent Stem Cells Promote Recovery of Murine Ischemic Limb Running title: Dar et al.; Human pluripotent stem cell-derived pericytes
نویسندگان
چکیده
Background-Pericytes represent a unique subtype of microvessel-residing perivascular cells
منابع مشابه
Multipotent vasculogenic pericytes from human pluripotent stem cells promote recovery of murine ischemic limb.
BACKGROUND Pericytes represent a unique subtype of microvessel-residing perivascular cells with diverse angiogenic functions and multilineage developmental features of mesenchymal stem cells. Although various protocols for derivation of endothelial and/or smooth muscle cells from human pluripotent stem cells (hPSC, either embryonic or induced) have been described, the emergence of pericytes in ...
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Background—Pericytes represent a unique subtype of microvessel-residing perivascular cells with diverse angiogenic functions and multilineage developmental features of mesenchymal stem cells. Although various protocols for derivation of endothelial and/or smooth muscle cells from human pluripotent stem cells (hPSC, either embryonic or induced) have been described, the emergence of pericytes in ...
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In the current issue of Circulation, Dar and colleagues report the healing of ischemic limbs in athymic mice by multipotent progenitors derived from human embryonic stem (ES) cells or reprogrammed adult cells. So far, nothing really original; the excitement comes from the demonstration that these ES cell and induced pluripotent stem cell (iPS)–derived regenerative units exhibit the features of ...
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