The Evolution of the ESRF's Structural Biology Beamlines
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چکیده
Structural Biologists are tackling ever more ambitious projects, for example more complex membrane proteins and larger macromolecular assemblies (Figure 1). Such systems often show considerable inter and intra crystal variation in diffraction quality. Sample evaluation prior to data collection, already widespread in Macromolecular Crystallography (Figure 2), will thus become more crucial as will data collection facilities optimised for the collection of diffraction data from crystals that are very small and/or diffract to low resolution (i.e. dmin 4 – 5 Å).
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