Management of Operable Breast Cancers When Patient Refuses Surgery
نویسندگان
چکیده
Surgery is the crucial modality of management in the multidisciplinary care of breast cancer. Without surgery the outcome of treatment is complicated and sub-optimal. The oncologists face dilemma when patient refuse for surgery or not operable due to patients medical condition. Here we describe two post-menopausal women with operable breast cancers those refused surgery. We managed these patients with induction chemotherapy, radical radiotherapy and hormonal therapy. Their serial radiological evaluation revealed complete disappearance of primary breast tumor and axillary lymph nodes at the end of 88 and 69 months post treatment with good cosmesis. Conservative management may be an option among post-menopausal women with operable breast cancers those refuse surgery. The controversial management of above cases has been discussed with review of literature.
منابع مشابه
State of the art in neoadjuvant therapy of breast cancer
Neoadjuvant therapy is no longer an option just for locally advanced operable cancers in order to facilitate breast-conserving surgery, but also for all early breast cancers when an indication for chemotherapy is given [1]. Pathological complete response (pCR) – defined as the absence of residual invasive or sometimes even in-situ cancer on breast and lymph nodes after preoperative therapy – ha...
متن کاملManagement of a Case of Mucor Colonization in Breast Tissue Expander Seroma Pocket
Mucormycosis has a mortality rate reaching 90%, and is imperative that therapy be initiated rapidly once a diagnosis is made. Successful treatment consists of management of underlying risk factors, surgical debridement, and antifungal therapies. The dilemma whether or not to pursue extensive debridement presents when the wound is cultured positive but the patient is not systemically ill.&...
متن کاملExploring patient experiences of neo-adjuvant chemotherapy for breast cancer.
BACKGROUND AND PURPOSE Neo-adjuvant chemotherapy is recommended for 'inoperable' locally advanced and inflammatory breast cancers. For operable breast cancers, trials indicate no survival differences between chemotherapy given pre or post-surgery. Communicating evidence based information to patients is complex and studies examining patient experiences of neo-adjuvant chemotherapy are lacking. T...
متن کاملOestrogen receptor negative early operable primary breast cancer in older women—Biological characteristics and long-term clinical outcome
BACKGROUND Older women are at the greatest risk of breast cancer development and a considerable number present with comorbidities. Although the majority of breast cancers in this age group express oestrogen receptor (ER), which makes endocrine therapy (primary or adjuvant) feasible, given the huge size of the elderly population, there remains a significant number of patients, in absolute term, ...
متن کامل