Leucocyte Variation, an Insight of Host Defenses During Hymenolepiasis and Restoration with Praziquantel
نویسندگان
چکیده
Haematological studies in helminthiasis reveal drastic alterations in the white blood cells (leucocytes), and its various components like neutrophils, lymphocytes, monocytes and eosinophils. The use of proper anthelmintic agent, restores normalcy in the infected host. These variations during helminth infections reflect the host defense status in combating the parasitic attack. The present study involves the evaluation of these total and differential haematological alterations, induced in the laboratory mouse Mus musculus, infested with the intestinal helminth, Hymenolepis nana (dwarf tapeworm), and treated with the praziquantel, using an automatic Coulter Counter.
منابع مشابه
Histopathological Assay of Induced Hymenolepiasis in Mus Musculus and Restoration of Normalcy with Praziquantel
The diversified modes of survival are the outcome of the struggle for existence which necessitates the exploration of various habitats resulting in the exploitation of the available resources. Parasitism is one such mode of survival and Cestode helminths are one such class of parasites which have adapted to virtually every tissue, organ and space in the body of both vertebrates and invertebrate...
متن کاملCorrelation of Hyperglycemia and Succinate dehydrogenase Activity During Hymenolepiasis in Mice and Treatment With Praziquantel
Energy metabolism is the chief controlling factor of all living organisms, mostly by the breakdown of glucose. The higher energy demands in a traumatized host directly affects levels of glucose and the enzyme activity involved in its ultimate breakdown. The variations in the carbohydrate levels of host Mus musculus infected with the intestinal helminth Hymenolepis nana and treated with anthelmi...
متن کاملDeworming Campaign in Eastern Afghanistan – Prevalence of Intestinal Parasites and Adoption of Treatment Strategy
Purpose: To estimate the prevalence and species of intestinal parasites in an Afghan community as well as to establish appropriate treatment method for each of the detected pathogens. Methods: Parasitological examination of stool samples collected from 777 children aged 1-17 years, treated in Ghazni Provincial Hospital (eastern Afghanistan) conducted in the period 2012 2013 made it possible to ...
متن کاملPraziquantel Treatment in Trematode and Cestode Infections: An Update
Status and emerging issues in the use of praziquantel for treatment of human trematode and cestode infections are briefly reviewed. Since praziquantel was first introduced as a broadspectrum anthelmintic in 1975, innumerable articles describing its successful use in the treatment of the majority of human-infecting trematodes and cestodes have been published. The target trematode and cestode dis...
متن کاملHypersensitivity (PCA and DTH) Response in H. diminuta Infected Mice, Treated with Praziquantel and Ivermectin
The objective of this study was to investigate the immunomodulatory efficacy of drugs (Praziquantel and Ivermectin) in Hymenolepis diminuta infected mice. The drugs were administrated to the infected mice on 13 , 14 and 15 post infection days. The immunomodulation due to test drugs was observed th th th on PCA and DTH response. PCA and DTH reactions were found to be directly proportional to the...
متن کامل