Effect of hyperthermia on experimental choroidal melanoma.

Choroidal melanoma: natural history and management options.

BACKGROUND Choroidal melanoma is the most common primary malignancy of the eye. Enucleation has been the mainstay of treatment, but new and more effective options have recently been proposed as eye- and vision-sparing alternatives. METHODS We reviewed the medical literature for trials and case reports involving the evolution, current uses, and limitations of alternatives to enucleation for tr...

Fulminant hepatic failure due to metastatic choroidal melanoma

Effect of Magnetic Fluid Hyperthermia on Implanted Melanoma in Mouse Models

Background: Nowadays, magnetic nanoparticles (MNPs) have received much attention because of their enormous potentials in many fields such as magnetic fluid hyperthermia (MFH). The goal of hyperthermia is to increase the temperature of malignant cells to destroy them without any lethal effect on normal tissues. To investigate the effectiveness of cancer therapy by magnetic fluid hyperthermia, Fe...

Laser and proton radiation to reduce uveal melanoma-associated exudative retinal detachments.

PURPOSE To assess whether laser-induced hyperthermia in conjunction with proton irradiation of choroidal melanoma may more rapidly decrease exudative retinal detachments. DESIGN Case-control study. METHODS This was a single-center prospective phase 1 study of choroidal melanoma patients with exudative retinal detachments. These tumors did not overhang the optic disc, involve the fovea, or h...

Local treatment failure after globe-conserving therapy for choroidal melanoma

Local treatment failure after globe-conserving therapy for choroidal melanoma is a surgical complication with significant morbidity to the vision and eye. Few reports in the literature have addressed this complication exclusively. A review of the published literature with reference to local treatment failure in the management of choroidal melanoma was performed to make known the potential diffe...