Solid-state extraction of cortisol from plasma or serum for liquid chromatography.

نویسندگان

  • B T Hofreiter
  • A C Mizera
  • J P Allen
  • A M Masi
  • W C Hicok
چکیده

Solid-state extraction of plasma or serum offers significant advantages over traditional liquid-liquid methods in cortisol determinations by liquid chromatography (HPLC). Sample preparation is facilitated and HPLC column contamination is minimized. Extract yield from the solid-state columns is enhanced by sample pretreatment with methanol. Cortisol values by solid-state extraction/HPLC correlate well (r = 0.92) with those from a commercial radioimmunoassay procedure.

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عنوان ژورنال:
  • Clinical chemistry

دوره 29 10  شماره 

صفحات  -

تاریخ انتشار 1983