A biomimetic total synthesis of (+)-ainsliadimer A.
نویسندگان
چکیده
A protecting group free and biomimetic total synthesis of (+)-ainsliadimer A has been accomplished in 14 steps from α-santonin. The synthesis relies on a hydrogen bonding promoted [4 + 2]-hetero-Diels-Alder dimerization to afford the key homodimer intermediate, which demonstrates the feasibility of using nonenzymatic conditions to achieve the proposed biosynthesis.
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ورودعنوان ژورنال:
- Organic letters
دوره 12 19 شماره
صفحات -
تاریخ انتشار 2010