Barx 1 and Sox 9 during
نویسندگان
چکیده
Thimios A. Mitsiadis1,2, Marie-Laurence Mucchielli1, Expression of the Sylva Raffo2, Jean-Pierre Proust2, Peter Koopman3 and Christo Goridis1 transcription factors Otlx2, 1Laboratoire de Génétique et Physiologie du Développement, IBDM, Campus de Luminy case 907, 2IMEB EA 2198, Faculté Barx1 and Sox9 during d’Odontologie, Université de la Méditerranée, Marseilles, France, and 3Centre for Molecular and Cellular Biology, The University of Queensland, Brisbane, mouse odontogenesis Australia
منابع مشابه
Sox-9 Is Expressed in Adult Articular Chondrocytes in Vivo and in Vitro, but Is Notcorrelated to the Regulation of Collagen Type Ii
Introduction: Anabolic activity is a crucial activity in articular chondrocytes and its failure is one major reason of osteoarthritic cartilage degeneration. Unclear are the intracellular factors responsible for upand down regulation of the molecules of interest. In this respect, the transcription factor Sox-9, a member of the HMG-domain transcription factor family, elicited much of interest as...
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Chondrocytes' hypertrophy includes metabolic changes, matrix remodelling, proliferation and apoptosis, characteristics associated with the progression of osteoarthritis. We investigated a possible association among Runt-related transcription factor 2 (RUNX-2), SOX-9 and fibroblast growth factor (FGF)-23 mRNA expressions in articular chondrocytes in order to elucidate their contribution in the o...
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The Y chromosomal switch gene SRY, which initiates testis development during mammalian embryogenesis was recently described (l).The SRY-encoded protein contains a 79 amino acid DNA-binding motif referred to as an HMG-box (2) known to exist in other transcription factors or proteins involved in DNA bending (3). On the basis of the homology between their HMGboxes, other SRY-related genes have bee...
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Genes of the Sox family encode evolutionarily conserved HMG box containing transcription factors, which play key roles in various events of cell determination/differentiation during development. The total number of Sox genes in Drosophila melanogaster was estimated to be eight, after classical molecular cloning approaches and exhaustive screening of the complete Drosophila genome. Here we repor...
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