Physiological Evidence of an Inverse Correlation between the Gonadal Function and Rfrp-3 Neurons in Mice
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چکیده
*Corresponding Author: Dr. Sumit Sethi, Ph.D. Interdisciplinary Laboratory for Clinical Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo UNIFESP, Building Research II, São Paulo, SPBrazil. 4022 PHYSIOLOGICAL EVIDENCE OF AN INVERSE CORRELATION BETWEEN THE GONADAL FUNCTION AND RFRP-3 NEURONS IN MICE Sumit Sethi* and Chandra Mohini Chaturvedi Interdisciplinary Laboratory for Clinical Neuroscience (LiNC), Department of Psychiatry, Universidade Federal de São Paulo – UNIFESP, São Paulo, BRAZIL. Department of Zoology, Banaras Hindu University, Varanasi 221 005, INDIA
منابع مشابه
Age-dependent variation in the RFRP-3 neurons is inversely correlated with gonadal activity of mice.
The present study analyzed changes in the expression of RFamide-related peptide-3 (RFRP-3; a mammalian ortholog of avian gonadotropin-inhibitory hormone), in the brain and correlated it with testicular activity of mice of different age groups (day-old, 1-, 3-, 5-, 7-, 9-, 11-, 13-week and 1.5-year-old). Testicular activity after a progressive increase up to 13-week of age declined in the old mi...
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RFamide-related peptide-3 (RFRP-3) [mammalian ortholog to gonadotropin-inhibiting hormone (GnIH)] potently inhibits gonadotropin secretion in mammals. Studies of RFRP-3 immunoreactivity and Rfrp expression (the gene encoding RFRP-3) in mammalian brains have uncovered several possible pathways regulating RFRP-3 neurons, shedding light on their potential role in reproduction and other processes, ...
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