Experiences with a new oral mercurial diuretic; merpurate.
نویسندگان
چکیده
OU RAL administration of diuretics with a safe and satisfactory diuresis has always been a therapeutic goal. Diuresis could then be accomplished at a slow but regular rate, with the avoidance of a sudden profuse diuresis,' which is very uncomfortable for the patient, and produces marked alteration of the fluid and electrolyte balance. Rapid diuresis has been known to cause attacks of gout,2 tetany,3 and cerebral thrombosis.4 It has caused the low salt syndrome, and overdigitalization. Hence, slow diuresis is of some importance. Furthermore, oral diuretics avoid the necessity of frequent visits to the doctor and the financial burden thereof. They also eliminate the distasteful injections and allow the patient to handle his own care within safe limits. The general recognition of the need of a safe and good oral diuretic without undesirable side effects is shown by the great number that have appeared upon the therapeutic scene in a relatively short span of time.
منابع مشابه
A NEW ORAL MERCURIAL DIURETIC - MERPURATE TABLE 4 . - Dog
OU RAL administration of diuretics with a safe and satisfactory diuresis has always been a therapeutic goal. Diuresis could then be accomplished at a slow but regular rate, with the avoidance of a sudden profuse diuresis,' which is very uncomfortable for the patient, and produces marked alteration of the fluid and electrolyte balance. Rapid diuresis has been known to cause attacks of gout,2 tet...
متن کاملA New Oral Mercurial Diuretic - Merpurate Table
OU RAL administration of diuretics with a safe and satisfactory diuresis has always been a therapeutic goal. Diuresis could then be accomplished at a slow but regular rate, with the avoidance of a sudden profuse diuresis,' which is very uncomfortable for the patient, and produces marked alteration of the fluid and electrolyte balance. Rapid diuresis has been known to cause attacks of gout,2 tet...
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OU RAL administration of diuretics with a safe and satisfactory diuresis has always been a therapeutic goal. Diuresis could then be accomplished at a slow but regular rate, with the avoidance of a sudden profuse diuresis,' which is very uncomfortable for the patient, and produces marked alteration of the fluid and electrolyte balance. Rapid diuresis has been known to cause attacks of gout,2 tet...
متن کاملClinical evaluation of a new oral nonmercurial diuretic.
The oral administration of the organomercurial drugs in patients requiring prolonged management of congestive failure has been rather unsatisfactory because of occasional toxic signs and symptoms. With the development of the pyrimidinedione derivatives as diuretic agents and encouraging pharmacologic studies in animals, clinical trial is warranted. A group of 24 patients who had received inject...
متن کاملThe Prolonged Use of an Oral Mercurial Diuretic in Ambulatory Patients with Congestive Heart Failure
Tablets of an oral mercurial diuretic were utilized in the management of patients with severe congestive failure over a prolonged period of time. The need for parenteral mercurial diuretics wvas eliminated or greatly decreased by this therapy. The individual dosage was established by clinical trial. _Minor toxic effects were encountered in several patients but in all instances it was p)ossible ...
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ورودعنوان ژورنال:
- Circulation
دوره 12 1 شماره
صفحات -
تاریخ انتشار 1955