What was the cause of Franklin Delano Roosevelt's paralytic illness?
نویسندگان
چکیده
In 1921, when he was 39 years of age, Franklin Delano Roosevelt contracted an illness characterized by: fever; protracted symmetric, ascending paralysis; facial paralysis; bladder and bowel dysfunction; numbness; and dysaesthesia. The symptoms gradually resolved except for paralysis of the lower extremities. The diagnosis at the onset of the illness and thereafter was paralytic poliomyelitis. Yet his age and many features of the illness are more consistent with a diagnosis of Guillain-Barré syndrome, an autoimmune polyneuritis. The likelihoods (posterior probabilities) of poliomyelitis and Guillain-Barré syndrome were investigated by Bayesian analysis. Posterior probabilities were calculated by multiplying the prior probability (disease incidence in Roosevelt's age group) by the symptom probability (likelihood of a symptom occurring in a disease). Six of eight posterior probabilities strongly favoured Guillain-Barré syndrome.
منابع مشابه
Assessment of Franklin D. Roosevelt’s Paralytic Illness
Franklin D. Roosevelt’s (FDR’s) paralytic illness was diagnosed as poliomyelitis. Some of his symptoms, such as fever and motor neuron infection are consistent with symptoms typical of this condition. However, recent research has led to the insight that he possibly suffered from Guillain-Barré syndrome instead. Through Bayesian analysis on his paralytic symptoms, researchers were able to argue ...
متن کاملEconomic class and popular support for franklin roosevelt in war and peace.
History has judged FDR as one of America's greatest leaders in part because he maintained the public's confidence in seeing the nation through the travails of the Depression and World War II. During this era, the two most widely employed explanatory variables in contemporary presidential popularity scholarship-the economy and war-assumed their most extreme values of the twentieth century. Hence...
متن کاملRevisiting the death of Eleanor Roosevelt: was the diagnosis of tuberculosis missed?
Controversy has surrounded the death of Eleanor Roosevelt in 1962. There has been a persistent sense that doctors missed the diagnosis of miliary tuberculosis, thereby jeopardizing her life. This article, using Roosevelt's medical chart and other previously unreviewed documents, revisits her illness and death. What disease actually killed Eleanor Roosevelt? Did her physicians miss the diagnosis...
متن کامل“Deficits Don’t Matter”: Abundance, Indebtedness and American Culture
If deficits, nor defaults, don't really matter anymore, what sign of our times is it? What has changed from the days that Franklin Delano Roosevelt risked the fragile economic recovery from the great depression by returning, in 1937, to the standard of his economic orthodoxy, a belief in fiscal rectitude and anaversion to debts and deficits? If that was a sign of a certain American character, w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of medical biography
دوره 11 4 شماره
صفحات -
تاریخ انتشار 2003