Antioxidant Potential of the Ethanol Extract of the Leaves of Vitex Negundo L
نویسندگان
چکیده
The antioxidant potential of the ethanol extract of Vitex negundo L. was evaluated by using 1, 1diphenyl-2-picrylhydrazyl (DPPH), hydrogen peroxide, total antioxidant capacity and erythrocyte (RBC) membrane stabilization assays. The extract showed significant activities in all antioxidant assays compared to the reference antioxidant ascorbic acid in a dose dependent manner. In DPPH and hydrogen peroxide scavenging assays the IC50 values of the extract were found to be 178.43 jig/mL and 158.93 jig/mL, respectively. Total antioxidant activity was also increased in a dose dependent manner. The ethanol extract of V. negundo also significantly protect the lyses of red blood corpuscles by stabilizing the membrane in hypotonic medium. These results suggest that V. negundo may act as a chemopreventative agent, providing antioxidant properties and offering effective protection from free radicals.
منابع مشابه
Comparative Evaluation of Polyphenol Contents and Antioxidant Activities between Ethanol Extracts of Vitex negundo and Vitex trifolia L. Leaves by Different Methods
The in vitro antioxidant potential assay between ethanolic extracts of two species from the genus Vitex (Vitex negundo L. and Vitex trifolia L.) belonging to the Lamiaceae family were evaluated. The antioxidant properties of different extracts prepared from both plant species were evaluated by different methods. DPPH scavenging, nitric oxide scavenging, and β-carotene-linoleic acid and ferrous ...
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