Tetrazolium compounds: synthesis and applications in medicine.
نویسندگان
چکیده
Tetrazoles represent a class of five-membered heterocyclic compounds with polynitrogen electron-rich planar structural features. This special structure makes tetrazole derivatives useful drugs, explosives, and other functional materials with a wide range of applications in many fields of medicine, agriculture, material science, etc. Based on our research works on azoles and other references in recent years, this review covers reported work on the synthesis and biological activities of tetrazole derivatives.
منابع مشابه
Uranyle Complexes: synthesis, evaluation of biological activity
In this research, some of the inorganic complexes of uranyl with N- donor ligandswere synthesized. Complexes were characteriezed by FT-IR and UV spectra, ¹HNMR,¹³CNMR and some physical properties. The uranyl unit (UO2) is composed of a center ofuranium atom with the charge (+6) and two oxygen atom by forming two U=O double bonds.The structure is linear (O=U=O, 180) and usually stable. So other ...
متن کاملReview on Biological Synthesis of Nano-Hydroxyapatite and Its Application in Nano-Medicine
Hydroxyapatite (HA) has many applications in medicine, dentistry, diagnosis, drug delivery systems, sewage treatment, bone remodeling, concentrating bacteria, covering implants, and antibacterial activity. Despite the numerous current applications of calcium phosphate compounds, particularly HA, their producing methods are being investigated to find the best processes. Several chemical and biol...
متن کاملمروری بر روش‌های سنتز آلکیل‌آزیدها و کاربردهای آنها در صنایع نظامی
Azide compounds have vast applications in military and civilian industries. Some of their applications include use in drug or drug intermediate production, macro cyclic polymer production through click reaction, automobile airbag production, energetic binders such as GAP, oxidizer, plasticizer and burning rate control additive in solid composite propellants. Due to the wide range of appli...
متن کاملRecent Applications of Meldrum's Acid in Organic Synthesis
Reactions of Meldrum's acid and its derivatives in view of their application in synthesis of diaminofurans,ketenimines, amidoesters, triamides, and diionic compounds, observed during the last decade in our laboratory,are reviewed.
متن کاملSynthesis and Biological Evaluation of 2-isonicotinyl 3, 5-diaryl -2h-(3-tetrazolium) Chloride Derivatives
A synthesis of 2-Isonicotinyl 3, 5-diaryl -2H-(3-tetrazolium) chloride (5) was performed starting from isonicotinic hydrazide (1). The treatment of 1 with various substituted aromatic aldehydes afforded the corresponding Schiff’s bases 3. The Schiff’s bases are converted into a series of aryl formazan via diazocoupling which underwent cyclization in the presence of H2O2 and KMnO4 to give substi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Molecules
دوره 20 4 شماره
صفحات -
تاریخ انتشار 2015