Flagella-driven Liposomes: Liposomes Actuated by Attached Flagella
نویسندگان
چکیده
In this study, we attached flagella to liposomes for enhancing liposome mobility (Figure 1 and 2). The flagella were detached from a biflagellate unicellular alga, Chlamydomonas (Chlamydomonas oda12-lc2-bccp), and they were then chemically bonded to the surface of the liposome. We found the mobility of liposomes with flagella was higher than that of liposomes without flagella by measuring a diffusion coefficient of the liposomes with/without flagella. Also, it was suggested that the liposomes with lower fluidity due to annexin-coating has higher mobility than non-coating one. We believe that liposomes with flagella can be utilized as high-mobility delivery vehicles to carry materials and drugs in a micrometer-sized space such as a microchip and a human body.
منابع مشابه
Cell-free synthesis of the torque-generating membrane proteins, PomA and PomB, of the Na+-driven flagellar motor in Vibrio alginolyticus.
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