Antimicrobial activities of different bioceramic root canal sealers on various bacterial species

Objective: The aim of the present study was to evaluate the antimicrobial activity of new bioceramic root canal sealers Smartpaste Bio, MTA Fillapex and AH plus. Materials and Methods: The antimicrobial activity of sealers was tested by agar diffusion method on the surface of agar plates of Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans and Escherichia coli. The sealers were placed into the prepared well on the agar plates. The diameters of the inhibition zones were measured after incubation for 24, 48, 72 hours. The data were analyzed statistically by ANOVA and Duncan’s tests at 5% significance level. Results: All tested sealers had antimicrobial effect against to test microorganisms. Smartpaste Bio had the biggest inhibition zone and the lowest had by MTA Fillapex and there was statistically difference between Smartpaste Bio and MTA Fillapex (p<0.05). The mean of inhibition zones was decreased in order 24, 48, 72 h time intervals for each group. There was statistically significant difference between 24 and 72 h mean of inhibition zone measurements (p<0.05). Conclusion: In comparison, all tested substance exhibited antimicrobial effect on standard strains however Smartpaste Bio had the biggest inhibition zone measurement than the other groups.