The microbiome revolution.

A Review of The Role of The Microbiome on Immune Responses and Its Association With Cystic Fibrosis

In recent years, the microbiome has been recognized as a key regulator of immune responses. Evidence suggests that changes in the microbiome can lead to chronic disease and even exacerbation of the disease. Impairment of innate immunity resulting from microbial incompatibility may worsen host susceptibility to infection and exacerbate chronic lung diseases. Specific microbes play a key role in ...

Human Microbiome

Humans are almost identical in their genetic pattern, but the slight differences in our DNA lead to remarkable phenotypic variation among the human population. There are a variety of microbial communities and their genes (microbiomes) in the human body that play an essential role in human health and disease. The microbes inhabiting our bodies is quite a bit more variable, with only a third of i...

Next Generation Sequencing and its Application in the Study of Microbiome in Plant Diseases Suppressive Soils

Progress in next-generation sequencing has played a significant role in ecological studies of microbial populations. These advances have led to a rapid evaluation in metagenomics studies (analysis of DNA of microbial communities without the need to culture). Many statistical and computational tools and metagenomics databases have led to the discovery of huge amounts of data. In this research, i...

A Metagenomic Analysis of Lung Microbiome in Chemically Injured and Healthy Individuals

Background and Aim: The role of the lung microbiome in respiratory complications associated with chemicals such as sulfur mustard or chlorine gas has yet to be determined. The aim of this study was to compare the structure and composition of the lung microbiome in chemically injured and healthy individuals in order to understand the relation between the population of the lung microbiota and res...

Microbiome Data Science: Understanding Our Microbial Planet.

Microbiology is experiencing a revolution brought on by recent developments in sequencing technology. The unprecedented volume of microbiome data being generated poses significant challenges that are currently hindering progress in the field. Here, we outline the major bottlenecks and propose a vision to advance microbiome research as a data-driven science.

Proteomics: A Revolution in the Evaluation of Gastrointestinal Microflora