Non-nucleoside structures retain full anti-HCMV potency of the dideoxy furanopyrimidine family.
نویسندگان
چکیده
We have recently reported that 2',3'dideoxy analogues of our exquisitely potent anti-VZV furanopyrimidine deoxynucleosides are shifted to selective anti-HCMV agents. We now find that the fully deoxygenated 2',3',5'-trideoxy analogue is fully antivirally active. This is taken as proof that these agents act by a novel non-nucleoside mechanism of action.
منابع مشابه
Efficacy and selectivity of some nucleoside analogs as anti-human cytomegalovirus agents.
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ورودعنوان ژورنال:
- Antiviral chemistry & chemotherapy
دوره 15 6 شماره
صفحات -
تاریخ انتشار 2004