Deformed Toric Ideal Constraints for Stoichiometric Networks

نویسندگان

  • Masamichi Sato
  • Kenji Fukumizu
چکیده

We discuss chemical reaction networks and metabolic pathways based on stoichiometric network analysis, and introduce deformed toric ideal constraints by the algebraic geometrical approach. With the deformed toric ideal constraints, the shape of flux is constrained without introducing ad hoc constraints. To illustrate the effectiveness of such constraints, we discuss two examples of chemical reaction network and metabolic pathway; in the former the shape of flux is constrained completely by deformed toric ideal constraints, and in the latter, it is shown the deformed toric ideal constrains the parameters of flux at least partially.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Convex and toric geometry to analyze complex dynamics in chemical reaction systems

DISSERTATION zur Erlangung des akademischen Grades doctor rerum naturalium Dedicated to the memory of KARIN GATERMANN Table 1: List of mathematical symbols C field of complex numbers R field of real numbers Z ring of integer numbers C[x] ring of polynomials with coefficients in the field of complex numbers I ideal I def, tor deformed toric ideal V (I) variety of an ideal V (I def, tor) variety ...

متن کامل

MAPK's networks and their capacity for multistationarity due to toric steady states.

Mitogen-activated protein kinase (MAPK) signaling pathways play an essential role in the transduction of environmental stimuli to the nucleus, thereby regulating a variety of cellular processes, including cell proliferation, differentiation and programmed cell death. The components of the MAPK extracellular activated protein kinase (ERK) cascade represent attractive targets for cancer therapy a...

متن کامل

The classification of smooth toric weakened Fano 3-folds

We completely classify toric weakened Fano 3-folds, that is, smooth toric weak Fano 3-folds which are not Fano but are deformed to smooth Fano 3-folds. There exist exactly 15 toric weakened Fano 3-folds up to isomorphisms.

متن کامل

MATHEMATICAL ENGINEERING TECHNICAL REPORTS Indispensable monomials of toric ideals and Markov bases

Extending the notion of indispensable binomials of a toric ideal ([14], [7]), we define indispensable monomials of a toric ideal and establish some of their properties. They are useful for searching indispensable binomials of a toric ideal and for proving the existence or non-existence of a unique minimal system of binomials generators of a toric ideal. Some examples of indispensable monomials ...

متن کامل

Indispensable monomials of toric ideals and Markov bases

Extending the notion of indispensable binomials of a toric ideal ((14), (7)), we define indispensable monomials of a toric ideal and establish some of their properties. They are useful for searching indispensable binomials of a toric ideal and for proving the existence or non-existence of a unique minimal system of binomials generators of a toric ideal. Some examples of indispensable monomials ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012