Synthesis of immunoglobulin heavy and light chains by the free ribosomes of a mouse plasma cell tumor.
نویسندگان
چکیده
Free and membrane-bound ribosomes have been isolated from a mouse plasma cell tumor secreting immunoglobulins, and allowed to synthesize proteins under cell-free conditions. Analysis of the products of synthesis by autoradiography of immunoelectrophoresis and peptide maps indicates that both types of ribosomes synthesize heavy and light immunoglobulin chains.
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 66 2 شماره
صفحات -
تاریخ انتشار 1970