Emerging concept of tailored lymphadenectomy in endometrial cancer
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منابع مشابه
Tailoring lymphadenectomy according to the risk of lymph node metastasis in endometrial cancer.
It has been strongly suggested that patients with endometrial cancer with low risk of lymph node metastasis do not benefit from lymphadenectomy and that intermediate-risk/high-risk endometrial cancer patients benefit from complete pelvic and para-aortic lymphadenectomy. This hypothesis needs to be validated by prospective studies. For randomized controlled trials (RCT), heterogeneity of interve...
متن کاملLower-LimbDrainageMapping for LymphedemaRiskReduction AfterPelvic Lymphadenectomy forEndometrial Cancer
Objectives. Pelvic lymphadenectomy is associated with a significant risk of lower-limb lymphedema. In this proof-of-concept study, we evaluated the feasibility of identifying the lower-limb drainage nodes (LLDNs) during pelvic lymphadenectomy for endometrial cancer. Secondary objectives were tomap lower-limbdrainageand toassess thediagnostic value of ourmapping technique. Methods. This prospect...
متن کاملSentinel lymph node mapping for endometrial cancer: a modern approach to surgical staging.
Most patients with endometrial cancer will present with early-stage disease. Although the rate of metastasis in these patients is low, proffering excellent prognoses, the standard of treatment in many practices still includes a complete or selective pelvic and para-aortic lymphadenectomy for staging; and accurate surgical staging is the most important prognostic factor. Many patients will under...
متن کاملLymphadenectomy for endometrial cancer: the controversy.
Comprehensive surgical staging for endometrial cancer, including hysterectomy, bilateral salpingo-oophorectomy, pelvic washings, and pelvic–aortic lymphadenectomy, defines disease biology and facilitates triage of tailored adjuvant therapy. Recent publication of two randomized trials has cracked the foundation of the house lived in by those believing in the absolute value of endometrial cancer ...
متن کاملSystematic lymphadenectomy for survival in patients with endometrial cancer: a meta-analysis.
OBJECTIVE The efficacy of systematic lymphadenectomy is controversial for improving overall survival in patients with endometrial cancer. Thus, we performed a meta-analysis comparing the efficacy for overall survival between systematic and unsystematic lymphadenectomies. METHODS After an extensive literature search between January 2000 and August 2010, we analyzed nine studies (two randomized...
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