Novel Balanced Translocation ( 4 ; 20 ) with Recurrent Spontaneous Abortion - - A Case Report
نویسندگان
چکیده
Chromosomal abnormalities are one of the major causes of infertility in man and woman. A couple with history of recurrent spontaneous abortion (RSA) was referred to our laboratory for chromosomal analysis. The analysis revealed normal 46,XY karyot ype in male and a novel balanced translocation 46,XXt(4;20)(q11;p13) in female partner. This translocation with breakpoints has not been reported in the literature particularly with RSA.
منابع مشابه
Balanced Chromosomal Rearrangement in Recurrent Spontaneous Abortions: A Case Report
One of the major causes of spontaneous abortion before the fourth month of pregnancy is chromosomal abnormalities. We report an unusual case of a familial balanced chromosomal translocation in a consanguineous couple who experienced 4 spontaneous abortions. Chromosomal studies were performed on the basis of G-banding technique at high resolution and revealed 46, XX, t (16 6) (p12 q26) and 46, X...
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Background: Spontaneous abortion (SAb) is the most common complication of early pregnancy. Numerous risk factors are associated with an increased risk of pregnancy loss such as: Maternally age, previous spontaneous abortion, prolonged ovulation to implantation, Gravidity, Interval Prolonged time to pregnancy, Balanced chromosomal translocations and Genetic disorders. The aim of this study was t...
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One of the major causes of spontaneous abortion before the fourth month of pregnancy is chromosomal abnormalities. We report an unusual case of a familial balanced chromosomal translocation in a consanguineous couple who experienced 4 spontaneous abortions. Chromosomal studies were performed on the basis of G-banding technique at high resolution and revealed 46, XX, t (16; 6) (p12; q26) and 46,...
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