Keilin, cytochrome, and the respiratory chain.
نویسنده
چکیده
منابع مشابه
Iron-sulphur clusters: agents of electron transfer and storage, and direct participants in enzymic reactions. Tenth Keilin memorial lecture.
dations. It is always with great respect that I look at the page of the pig-leather-bound book where guests and visitors of that Institute signed in (Fig. I ) . I did not know any of the participants, neither did I have the faintest notion that the field of biological oxidations would be the field of my main interest and endeavour for many years or that I would some day have the honour of lectu...
متن کاملThe Kinetics and Inhibition of Cytochrome Components of the Succinic Oxidase System
In the course of studies by Keilin and Hartree (1) on succinic oxidase preparation of heart muscle particles, it was observed that the kinetics of reduction of cytochrome b were not in accord with some rather fundamental criteria that must be met for an electron-transferring component in the respiratory chain (2). On the other hand, studies of the kinetics of cytochrome b in intact yeast cells ...
متن کاملEffect of cytochrome c on the generation and elimination of O2*- and H2O2 in mitochondria.
The primary recognized function of cytochrome c is to act as an electron carrier transferring electrons from complex III to complex IV in the respiratory chain of mitochondria. Recent studies on cell apoptosis reveal that cytochrome c is responsible for the programmed cell death when it is released from mitochondria to cytoplasm. In this study we present evidence showing that cytochrome c plays...
متن کاملThe spectral and enzymatic characterization of cytochrome c1 of liver mitochondria.
The presence of cytochrome cl as a part of the respiratory chain was first reported in 1940 by Yakushiji and Okunuki (1). They concluded from visual spectroscopic observations of heart muscle preparations that this hemoprotein mediates the reactions between cytochromes b and c, as well as between cytochromes b and a. The validity of Yakushiji and Okunuki’s work was questioned by Slater (2), who...
متن کاملKeilin's respiratory chain concept and its chemiosmotic consequences.
It was obviously my hope that the chemiosmotic rationale of vectorial metabolism and biological energy transfer might one day come to be generally accepted, and I have done my best to argue in favour of that state of affairs for more than twenty years. But, it would have been much too presumptuous to have expected it to happen. Of course, I might have been wrong, and in any case, was it not the...
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 278 19 شماره
صفحات -
تاریخ انتشار 2003