Variation of dengue NS1 antigen measured by commercial ELISA kit in various forms of dengue infections and assessment of the association between NS1 antigen level and disease severity

نویسندگان

  • Veasna Duong
  • Sowath Ly
  • Sivuth Ong
  • Norith Chroeung
  • Patrich Lorn Try
  • Vincent Deubel
  • Sirenda Vong
  • Philippe Buchy
چکیده

Background Dengue is a systemic infection with a wide clinical spectrum including asymptomatic, mild undifferentiated dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue with shock syndrome (DSS). Detection of dengue NS1 antigen (Ag) in acute infection is a valuable tool for early diagnosis. The purpose of this study was to evaluate the sensitivity of the Platelia NS1 Ag kit (BioRad®) for the various forms of DENV infection and assess the potential role of NS1 Ag as a marker of severity.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2011