Rigid-body docking of mdm2 antagonists
نویسندگان
چکیده
1. Rajamani D, Thiel S, Vajda S, Camacho C. Anchor residues in protein-protein interactions. PNAS 2004;101(31):1128711292 2. Kussie, P. H.; Gorina, S.; Marechal, V.; Elenbaas, B.; Moreau, J.; Levine, A. J.; Pavletich, N. P. Science 1996, 274, 948-953. 3. Ding K, Lu Y, Nikolovska-Coleska Z, Wang G, Qiu S, Shangary S, Gao W, Qin D, Stuckey J, Krajewski K, Roller PP, Wang S. Structure-based design of spirooxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction. J Med Chem 2006;49(12):3432-3435. 4. Moloc developed by Roche Biostructural Community. http://www.moloc.ch/ 5. ChemAxon Conformer Plugin a product of ChemAxon. http://www.chemaxon.com/ Rigid-body Docking
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