Gold(I)-catalyzed ring expansions of unactivated alkynylcyclopropanes to (e)-2-alkylidenecyclobutanamines in the presence of sulfonamides.
نویسندگان
چکیده
The ring expansion of cyclopropane derivatives provides a powerful method to construct synthetically useful four-membered carbocycles. Herein, a new type of gold(I)-catalyzed ring expansion of an unactivated alkynylcyclopropane/sulfonamide trapping strategy to (E)-2-alkylidenecyclobutanamines was described. The reaction tolerates a range of aryl and alkyl substituents with moderate to good yields.
منابع مشابه
Effects of haloniums on gold-catalyzed ring expansion of 1-oxiranyl-1-alkynylcyclopropanes.
We observed distinct chemoselectivities for the gold-catalyzed transformation of cis-1-oxiranyl-1-alkynylcyclopropanes 1 into various halogenated products in the presence of suitable Au(III) catalysts and N-halosuccinimide (halo = chloro, bromo and iodo).
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ورودعنوان ژورنال:
- Organic letters
دوره 12 4 شماره
صفحات -
تاریخ انتشار 2010