Selective formation of 1,5-substituted sulfonyl triazoles using acetylides and sulfonyl azides.
نویسندگان
چکیده
The reaction of acetylides with sulfonyl azides was found to selectively form 1,5-substituted sulfonyl triazoles. This reaction thus provides access to the regioisomeric product as compared to the popular copper-catalyzed azide-alkyne cycloaddition. The reaction is efficient and selective with a variety of alkyne sources and sulfonyl azides and can incorporate an additional electrophile to yield 1,4,5-trisubstituted sulfonyl triazoles.
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ورودعنوان ژورنال:
- Organic letters
دوره 13 12 شماره
صفحات -
تاریخ انتشار 2011